To include altitude effects, we recommend that you consult tables of atmospheric data to identify the static pressure and temperature based on a geometric and/or geopotential altitude. From the pressure and temperature, it is easy calculate the air density using the Ideal Gas equation. Enter this value in the Material Editor as a constant property for your fluid.
If constant properties are assumed (compressiblity and thermal effects are neglected) the density is the only parameter that needs to be changed on the Material Editor to define your fluid materials.
Note that the Reynolds number is the real effect that is evaluatied when solving at different altitudes.
You can also reference this attached excel document